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Diagnostic value of PIVKA-II and alpha-fetoprotein in hepatitis B virus-associated hepatocellular carcinoma

Screenshot 2023 01 27 175200

This study aims to determine the cutoff values and to compare the diagnostic role of alpha-fetoprotein (AFP) and prothrombin induced by vitamin K absence-II (PIVKA-II) in chronic hepatitis B (CHB).

Seo SI, Kim HS, Kim WJ, Shin WG, Kim DJ, Kim KH, Jang MK, Lee JH, Kim JS, Kim HY, Kim DJ, Lee MS, Park CK…

Diagnostic value of prothrombin induced by the absence of vitamin K or antagonist-II (PIVKA-II) for early stage HBV related hepatocellular carcinoma

model human liver made paper stethoscope

This study aims to evaluate the diagnostic efficacy of prothrombin induced by the absence of vitamin K or antagonist-II (PIVKA-II) for early stage hepatitis virus B (HBV) related hepatocellular carcinoma (HCC).

Wang X, Zhang W, Liu Y, Gong W, Sun P, Kong X, Yang M, Wang Z…

Hepatocellular carcinoma surveillance: current practice and future directions

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This review article provides a comprehensive overview of the indications and rationale for HCC surveillance, currently available surveillance methods and their utilization, effectiveness, and limitations, as well as novel surveillance tools which are emerging as alternatives.

Ahn JC, Lee YT, Agopian VG, Zhu Y, You S, Tseng HR, Yang J…

Protein induced by vitamin K absence or antagonist-II versus alpha-fetoprotein in the diagnosis of hepatocellular carcinoma: A systematic review with meta-analysis

Roche 10229

PIVKA-II has been extensively studied as a biomarker in HCC. However, its diagnostic capability varies across HCC studies. This study aimed to compare the performance of PIVKA-II with AFP in the diagnosis of HCC.

Xing H, Zheng YJ, Han J, Zhang H, Li ZL, Lau WY, Shen F, Yang T…

Diagnostic value of serum PIVKA-II levels for BCLC early hepatocellular carcinoma and correlation with HBV DNA

doctor performing medical research lab

This study aims to determine the clinical value of serum Prothrombin induced by vitamin K absence-II (PIVKA-II) in early hepatocellular carcinoma (HCC), and to explore its relationship with vascular invasion and HBV DNA.

Wu J, Xiang Z, Bai L, He L, Tan L, Hu M, Ren Y…

Leading the Way for HCC Surveillance and Diagnosis: Dr Bao Toan Nguyen

Dr Bao Toan Nguyen combating cancer

In this video, Dr Bao Toan Nguyen from MEDIC-LAB Ho Chi Minh discusses how PIVKA-II can complement AFP in assisting clinicians in the early detection and overall management of HCC, and his experience with PIVKA-II at MEDIC-LAB. …