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Protein induced by vitamin K absence or antagonist-II versus alpha-fetoprotein in the diagnosis of hepatocellular carcinoma: A systematic review with meta-analysis

Roche 10229

PIVKA-II has been extensively studied as a biomarker in HCC. However, its diagnostic capability varies across HCC studies. This study aimed to compare the performance of PIVKA-II with AFP in the diagnosis of HCC.

Xing H, Zheng YJ, Han J, Zhang H, Li ZL, Lau WY, Shen F, Yang T…

Diagnostic value of serum PIVKA-II levels for BCLC early hepatocellular carcinoma and correlation with HBV DNA

doctor performing medical research lab

This study aims to determine the clinical value of serum Prothrombin induced by vitamin K absence-II (PIVKA-II) in early hepatocellular carcinoma (HCC), and to explore its relationship with vascular invasion and HBV DNA.

Wu J, Xiang Z, Bai L, He L, Tan L, Hu M, Ren Y…

Leading the Way for HCC Surveillance and Diagnosis: Dr Bao Toan Nguyen

Dr Bao Toan Nguyen combating cancer

In this video, Dr Bao Toan Nguyen from MEDIC-LAB Ho Chi Minh discusses how PIVKA-II can complement AFP in assisting clinicians in the early detection and overall management of HCC, and his experience with PIVKA-II at MEDIC-LAB. …

Value of PIVKA-II in surveillance and treatment monitoring for patients with advanced HCC

Value of PIVKA II in surveillance and treatment monitoring for patients with advanced HCC

This presentation has 2 parts. In the first part of this presentation, Prof. Nobuharu Tamaki discusses the diagnostic utility of PIVKA-II in HCC, and the potential etiologies where PIVKA-II may be useful in surveillance and detection of HCC. In the second half, he discusses the correlation between PIVKA-II levels and treatment outcomes, and how PIVKA-II can potentially be used for treatment monitoring in HCC….

HCC Patient Journey and biomarkers’ roles in the HCC management

HCC Patient Journey and biomarkers roles in the HCC management 1

Detection of HCC at early stages remains a challenge, with less than 20% of patients being diagnosed at an early stage, when they can benefit from potentially curative therapies(1). In this presentation, Prof. Tawesak Tanwandee discusses the role of tumour markers for early diagnosis of HCC, as well as prognosis and response to treatment. …

The clinical utility of HCC algorithms as aids in the diagnosis of HCC

The clinical utility of HCC algorithms as aids in the diagnosis of HCC

In this presentation, Prof. Ming Lung Yu discusses the results of his study, which aims to address the diagnostic accuracy of HCC using Elecsys GAAD algorithmic score as compared to AFP and PIVKA-II, with or without the complementation of sonography. …