Prothrombin induced by vitamin K absence-II (PIVKA-II) was reported as a diagnosis and prognosis marker for hepatocellular carcinoma (HCC). This prospective study aims to comparatively verify Elecsys PIVKA-II and conventional Lumipulse PIVKA-II from the serum samples of patients with unresectable HCC undergoing systemic therapy.
Kaneko S, Kurosaki M, Tsuchiya K, Yasui Y, Hayakawa Y, Inada K, Tanaka Y, Ishido S, Kirino S, Yamashita K, Nobusawa T, Matsumoto H, Kakegawa T, Higuchi M, Takaura K, Tanaka S, Maeyashiki C, Tamaki N, Takahashi Y, Nakanishi H, Izumi N…
Cancer Type: Liver
Clinical evaluation of Elecsys PIVKA-II for patients with advanced hepatocellular carcinoma
APACMed White Paper – Strengthening Healthcare Systems Through the Critical Role of Diagnostics
Diagnostic technologies are used across the entire patient journey of multiple disease states, and provide the tools to prevent, detect, and monitor the required interventions. Despite its important role, diagnostics have been historically under prioritized. Read how APACMed seeks to improve the value recognition of diagnostic solutions.
Hardesty CL, Sarno R, Pelou C, Teng G, Aslam B, Bourcet A, Nair AKR, Wang J, Lina Y, Wearne D, Panth A, Rua C, Ho R, Kumar SA, Freitas E, Charafi N, Tan V, Chen JS, Veigas V, Teo P…
Analytical performance and method comparison of the Elecsys PIVKA-II immunoassay as an aid in diagnosis of hepatocellular carcinoma (HCC)
This study evaluates the analytical performance of the Elecsys PIVKA-II immunoassay to aid in HCC diagnosis, establish method-specific reference ranges in healthy individuals, and perform a method comparison versus commercially available platforms under routine laboratory conditions.
Chan HLY, Vogel A, Berg T, De Toni EN, Kudo M, Trojan J, Weinmann A, Eiblmaier A, Klein HG, Hegel JK, Morgenstern D, Madin K, Rolny V, Lisy MR, Piratvisuth T…
A comparative analysis of Elecsys GALAD and Elecsys GAAD score to detect early-stage hepatocellular carcinoma in an international cohort
This study compared the clinical performance of the Elecsys GALAD (gender [sex], age, alpha-fetoprotein [AFP] Lens culinaris agglutinin-reactive fraction of AFP [AFP-L3] and protein-induced by vitamin K absence-II [PIVKA-II]) and Elecsys GAAD (gender [sex], age, AFP and PIVKA-II) algorithms in differentiating hepatocellular carcinoma and benign chronic liver disease.
Chan HLY, Vogel A, Berg T, De Toni EN, Kudo M, Trojan J, Malinowsky K, Findeisen P, Klein HG, Hegel JK, Schöning W, Kröniger K, Madin K, Sharma A, Piratvisuth T
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My greatest hope | Mr Yan’s liver cancer story
Mr Yan was diagnosed with hepatocellular carcinoma (HCC) in 2018. He was a healthy, active person as a competitive skier, and his diagnosis was completely unexpected. With the support and love of his wife and son, Mr Yan has been able to remain hopeful. Hear his story here….
Hepatocellular carcinoma – the ‘silent killer’ disease infographic
Chronic liver disease (CLD) is on the rise. CLD can progress to Hepatocellular Carcinoma (HCC), a type of liver cancer. What are the risk factors for HCC, and how is it diagnosed and treated? Read this infographic to find out more. …