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Hepatocellular carcinoma – the ‘silent killer’ disease infographic

Chronic liver disease is on the rise1 which can progress to Hepatocellular Carcinoma (HCC), a type of liver cancer2. What are the risk factors for HCC and how is it diagnosed and treated?



  1. Moon Am, et al. Clin Gastroenterol Hepatol. 2019 Aug
  2. Omata et al. APASL guideline Hepatol Int (2017) 11:317–370
  3. WHO: Globocan 2018 – Liver cancer factsheet. [Internet; cited 2019 July 24] Available from:
  4. Llovet J, et al. Hepatocellular carcinoma. Nat Rev Dis Primers. 2016;2:16018.
  5. WHO: Globocan 2018 – China cancer factsheet. [Internet; cited 2019 July 24] Available from:
  6. Tanaka M, et al. Hepatitis B and C Virus Infection and Hepatocellular Carcinoma in China: A Review of Epidemiology and Control Measures. J Epidemiol. 2011;21(6):401-416.
  7. Medline. [Internet; cited 2019 July 24]. Available from:
  8. Giannini G, et al. Prognosis of untreated hepatocellular carcinoma. Hepatology. 2015;61(1):184-190.
  9. Medscape. [Internet; cited 2019 July 24]. Available from:
  10. Omata et al. APASL guideline Hepatol Int (2017_ 11:317-370)
  11. World Health Organization. The top 10 causes of death in 2015. WHO (2016).
  12. Wu Q, Qin S. Features and treatment options of Chinese hepatocellular Carcinoma. Chin Clin Oncol. 2013;2(4):38.
  13. Marrero K, Kulik L, et al. Diagnosis, staging, and management of hepatocellular carcinoma: 2018 practice guidance by the American Association for the Study of Liver Diseases. Hepatology. 2018;68(2):723-750.
  14. Zhao et al. Liver International 2018; 38: 503-514

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