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The fourth version of Clinical Practice Guidelines for Hepatocellular Carcinoma was revised by the Japan Society of Hepatology, according to the methodology of evidence-based medicine and partly to the Grading of Recommendations Assessment, Development, and Evaluation system, which was published in October 2017 in Japanese. New or revised recommendations were described, herein, with a special reference to the surveillance, diagnostic, and treatment algorithms.

Authors: Norihiro Kokudo, Nobuyuki Takemura, Kiyoshi Hasegawa, Tadatoshi Takayama, Shoji Kubo, Mitsuo Shimada, Hiroaki Nagano, Etsuro Hatano, Namiki Izumi, Shuichi Kaneko, Masatoshi Kudo, Hiroko Iijima, Takuya Genda, Ryosuke Tateishi, Takuji Torimura, Hiroshi Igaki, Satoshi Kobayashi, Hideyuki Sakurai, Takamichi Murakami, Takeyuki Watadani, Yutaka Matsuyama