HCV – Clinical Value of Diagnostics https://clinicalvalue.com Thu, 27 Mar 2025 04:16:10 +0000 en-US hourly 1 https://wordpress.org/?v=6.6.2 https://i0.wp.com/clinicalvalue.com/wp-content/uploads/2023/01/apple-touch-icon.png?fit=32%2C32&ssl=1 HCV – Clinical Value of Diagnostics https://clinicalvalue.com 32 32 225041835 APASL 2023 Taiwan Congress Report https://clinicalvalue.com/apasl-2023-taiwan-congress-report/ Wed, 31 May 2023 01:53:42 +0000 https://clinicalvalue.com/?p=6924 Catch up on the highlights of APASL 2023 with this congress report, covering session on hepatitis B, hepatitis C, hepatocellular carcinoma, and fatty liver disease. ...

The post APASL 2023 Taiwan Congress Report appeared first on Clinical Value of Diagnostics.

]]>

The post APASL 2023 Taiwan Congress Report appeared first on Clinical Value of Diagnostics.

]]> 6924 Impact of PIVKA-II in diagnosis of hepatocellular carcinoma https://clinicalvalue.com/impact-of-pivka-ii-in-diagnosis-of-hepatocellular-carcinoma/ Tue, 14 Mar 2023 09:05:07 +0000 https://clinicalvalue.com/?p=6522 This study was designed to investigate the potential role of PIVKA-II as a diagnostic, non-invasive marker for HCC at its early stages and to assess its sensitivity and specificity as compared with the usual recommended marker AFP.

Zakhary NI, Khodeer SM, Shafik HE, Abdel Malak CA...

The post Impact of PIVKA-II in diagnosis of hepatocellular carcinoma appeared first on Clinical Value of Diagnostics.

]]>

Quick Summary

Liver cancer grows silently with mild or no symptoms until advanced. In the absence of an effective treatment for advanced stage of hepatic cancer hope lies in early detection, and screening for high-risk population. Among Egyptians viral hepatitis is the most common risk factor for hepatocellular carcinoma (HCC).

This study was designed to determine the level of prothrombin induced by vitamin K absence-II (PIVKA-II) in sera of patients suffering from HCC to diagnose HCC at its early stage.

PIVKA-II proved to be superior to AFP for early detection of HCC patients being highly sensitive and specific. Furthermore it has the ability to discriminate between different histopathological grades of HCC and It has a powerful diagnostic validity to evaluate the thrombosis of portal vein and to differentiate between early and late stages of HCC. The direct relation between the level of PIVKA-II and the size of tumor makes it an attractive tool for early HCC diagnosis and surveillance. Using the best cut-off value of AFP (>28), showed a sensitivity of (44%) and specificity of (73.3%). While cut-off value of PIVKA-II (>53.7) showed 100% sensitivity and specificity.

Authors: Nadia I. Zakhary, Sherif M. Khodeer, Hanan E. Shafik, Camelia A. Abdel Malak

Access the full publication

The post Impact of PIVKA-II in diagnosis of hepatocellular carcinoma appeared first on Clinical Value of Diagnostics.

]]> 6522 Liver Disease in Asia Pacific: Insights from Prof Pierce Chow https://clinicalvalue.com/liver-disease-in-asia-pacific-insights-from-prof-pierce-chow/ Fri, 09 Dec 2022 09:13:11 +0000 http://apac-clinicalvalue-prod-lb-800083143.ap-southeast-1.elb.amazonaws.com/?p=6292 In this Q&A, Prof Pierce Chow of the National Cancer Centre Singapore discusses the epidemiology of liver disease in Asia Pacific; key considerations around the clinical management of common liver diseases like HBV, HCV, fatty liver and HCC; and the critical role of diagnostics in ensuring early detection and effective treatment....

The post Liver Disease in Asia Pacific: Insights from Prof Pierce Chow appeared first on Clinical Value of Diagnostics.

]]> The post Liver Disease in Asia Pacific: Insights from Prof Pierce Chow appeared first on Clinical Value of Diagnostics.

]]> 6292 Tackling HCV in Punjab: local experts share strategies for success https://clinicalvalue.com/tackling-hcv-in-punjab-local-experts-share-strategies-for-success/ Fri, 09 Dec 2022 09:06:27 +0000 http://apac-clinicalvalue-prod-lb-800083143.ap-southeast-1.elb.amazonaws.com/?p=6279 Punjab is one of Pakistan’s largest provinces and has a particularly high HCV prevalence rate of roughly 9%, compared to 5.4% for Pakistan’s total population. Hear from Prof Ghias Un Nabi Tayyab and Prof Muhammad Umar, two leading experts on HCV in pUnjab, and active participants in Pakistan’s HCV programmes, as they share their perspectives on Punjab’s HCV eradication efforts and solutions for local challenges. ...

The post Tackling HCV in Punjab: local experts share strategies for success appeared first on Clinical Value of Diagnostics.

]]> The post Tackling HCV in Punjab: local experts share strategies for success appeared first on Clinical Value of Diagnostics.

]]> 6279 Pakistan’s national HCV elimination programme: insights from Dr Huma Qureshi https://clinicalvalue.com/pakistans-national-hcv-elimination-programme-insights-from-dr-huma-qureshi/ Fri, 09 Dec 2022 09:01:32 +0000 http://apac-clinicalvalue-prod-lb-800083143.ap-southeast-1.elb.amazonaws.com/?p=6273 In 2019, Pakistan announced a nationwide programme to scale up HCV prevention, testing and treatment. Hear from gastroenterologist Dr Huma Qureshi, a key figure in Pakistan’s national HCV program, as she shares her thoughts on best practices for screening and elimination across the region. ...

The post Pakistan’s national HCV elimination programme: insights from Dr Huma Qureshi appeared first on Clinical Value of Diagnostics.

]]> The post Pakistan’s national HCV elimination programme: insights from Dr Huma Qureshi appeared first on Clinical Value of Diagnostics.

]]> 6273 Hepatitis C: the patient journey from screening to diagnosis and treatment https://clinicalvalue.com/hepatitis-c-the-patient-journey-from-screening-to-diagnosis-and-treatment/ Fri, 09 Dec 2022 09:00:04 +0000 http://apac-clinicalvalue-prod-lb-800083143.ap-southeast-1.elb.amazonaws.com/?p=6270 An estimated 71 million people around the world are chronically infected with hepatitis C virus (HCV), with a large proportion currently being undiagnosed or diagnosed late. There is an urgent need to identify them and link them to care. In this presentation, A/Prof Jeffrey Lazarus of the Faculty of Medicine at University of Barcelona, reviews the current innovative HCV testing initiatives, and the need for tailored, people-centered approaches to ultimately bring testing services closer to patients. ...

The post Hepatitis C: the patient journey from screening to diagnosis and treatment appeared first on Clinical Value of Diagnostics.

]]> The post Hepatitis C: the patient journey from screening to diagnosis and treatment appeared first on Clinical Value of Diagnostics.

]]> 6270 HCV screening in Egypt: key elements of a successful national screening programme https://clinicalvalue.com/hcv-screening-in-egypt-key-elements-of-a-successful-national-screening-programme/ Fri, 09 Dec 2022 08:57:57 +0000 http://apac-clinicalvalue-prod-lb-800083143.ap-southeast-1.elb.amazonaws.com/?p=6267 In 2018, the world’s largest HCV screening campaign was initiated in Egypt. Within 7 months following its initiation, 49.5 million people were screened; and 2.2 million HCV-seropositive individuals were referred for evaluation and treatment. In this article, take a closer look at Egypt’s HCV screening program, and learn about the key elements that contributed to its success. ...

The post HCV screening in Egypt: key elements of a successful national screening programme appeared first on Clinical Value of Diagnostics.

]]> The post HCV screening in Egypt: key elements of a successful national screening programme appeared first on Clinical Value of Diagnostics.

]]> 6267 HCV elimination in Sindh: insights from Prof Muhammad Sadik Memon and Dr Zaigham Abbas https://clinicalvalue.com/hcv-elimination-in-sindh-insights-from-prof-muhammad-sadik-memon-and-dr-zaigham-abbas/ Fri, 09 Dec 2022 06:36:01 +0000 http://apac-clinicalvalue-prod-lb-800083143.ap-southeast-1.elb.amazonaws.com/?p=6264 The province of Sindh has one of the world’s highest rates of HCV infection and bears the second highest disease burden of both HBV and HCV among all the provinces in Pakistan. Learn from Prof Muhammad Sadik Memon and Dr Zaigham Abbas, two prominent figures in the fight against HCV in Sindh province, about the challenges in diagnosing and treating HCV-related conditions and opportunities to address them. ...

The post HCV elimination in Sindh: insights from Prof Muhammad Sadik Memon and Dr Zaigham Abbas appeared first on Clinical Value of Diagnostics.

]]> The post HCV elimination in Sindh: insights from Prof Muhammad Sadik Memon and Dr Zaigham Abbas appeared first on Clinical Value of Diagnostics.

]]> 6264 HCV elimination in Pakistan: insights from Dr Zaigham Abbas https://clinicalvalue.com/hcv-elimination-in-pakistan-insights-from-dr-zaigham-abbas/ Fri, 09 Dec 2022 06:34:18 +0000 http://apac-clinicalvalue-prod-lb-800083143.ap-southeast-1.elb.amazonaws.com/?p=6261 Pakistan has one of the world’s highest rates of HCV infection. Learn from Dr Zaigham Abbas, Head of Gastroenterology at Ziauddin University Hospital and President of Pakistan Society for the Study of Liver Diseases (PSSLD), on the strategies to manage Pakistan’s HCV problem and his efforts to eliminate HCV in Pakistan. ...

The post HCV elimination in Pakistan: insights from Dr Zaigham Abbas appeared first on Clinical Value of Diagnostics.

]]> The post HCV elimination in Pakistan: insights from Dr Zaigham Abbas appeared first on Clinical Value of Diagnostics.

]]> 6261 HCV elimination in Northern Pakistan: Prof Aamir Khan on treating patients in KPK province and the Afghan borderlands https://clinicalvalue.com/hcv-elimination-in-northern-pakistan-prof-aamir-khan-on-treating-patients-in-kpk-province-and-the-afghan-borderlands/ Fri, 09 Dec 2022 06:30:05 +0000 http://apac-clinicalvalue-prod-lb-800083143.ap-southeast-1.elb.amazonaws.com/?p=6258 Pakistan has one of the world’s highest rates of HCV infection. It's no surprise that their healthcare systems face mounting pressure from HCV-related conditions. Learn from Prof Aamir Khan, Head of the Gastroenterology and Hepatology division at Lady Reading Hospital Peshawar, about his efforts to improve HCV care in KPK, Pakistan’s third largest province, including patients from Afghanistan who cross the border to seek treatment at his hospital....

The post HCV elimination in Northern Pakistan: Prof Aamir Khan on treating patients in KPK province and the Afghan borderlands appeared first on Clinical Value of Diagnostics.

]]> The post HCV elimination in Northern Pakistan: Prof Aamir Khan on treating patients in KPK province and the Afghan borderlands appeared first on Clinical Value of Diagnostics.

]]> 6258