Epidemiology – Clinical Value of Diagnostics https://clinicalvalue.com Wed, 20 Mar 2024 06:03:53 +0000 en-US hourly 1 https://wordpress.org/?v=6.6.2 https://i0.wp.com/clinicalvalue.com/wp-content/uploads/2023/01/apple-touch-icon.png?fit=32%2C32&ssl=1 Epidemiology – Clinical Value of Diagnostics https://clinicalvalue.com 32 32 225041835 Hepatocellular carcinoma surveillance: current practice and future directions https://clinicalvalue.com/hepatocellular-carcinoma-surveillance-current-practice-and-future-directions/ Mon, 13 Mar 2023 09:13:48 +0000 https://clinicalvalue.com/?p=6467 This review article provides a comprehensive overview of the indications and rationale for HCC surveillance, currently available surveillance methods and their utilization, effectiveness, and limitations, as well as novel surveillance tools which are emerging as alternatives.

Ahn JC, Lee YT, Agopian VG, Zhu Y, You S, Tseng HR, Yang J...

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Quick Summary

The global incidence and mortality rates of hepatocellular carcinoma (HCC) are alarmingly high. Timely detection of HCC through surveillance is crucial for individuals with cirrhosis or other high-risk conditions to improve their overall survival. Although biannual ultrasonography with or without alpha-fetoprotein is currently the standard method for HCC surveillance, it has limited sensitivity in early-stage disease and may not be effective for some individuals.

This review article aims to comprehensively examine the current state of HCC surveillance, including the reasons and criteria for conducting HCC surveillance, conventional methods for HCC surveillance, and their advantages and disadvantages. Additionally, the review will discuss alternative surveillance methods such as cross-sectional imaging and emerging circulating biomarkers, as well as the issue of under-utilization of HCC surveillance and the potential harms associated with it.

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