Disease Awareness – Clinical Value of Diagnostics https://clinicalvalue.com Thu, 27 Mar 2025 06:22:04 +0000 en-US hourly 1 https://wordpress.org/?v=6.6.2 https://i0.wp.com/clinicalvalue.com/wp-content/uploads/2023/01/apple-touch-icon.png?fit=32%2C32&ssl=1 Disease Awareness – Clinical Value of Diagnostics https://clinicalvalue.com 32 32 225041835 End-to-end liver disease management at Zhuhai People’s Hospital: Project Pearl https://clinicalvalue.com/end-to-end-liver-disease-management-at-zhuhai-peoples-hospital-project-pearl/ Wed, 04 Dec 2024 07:47:45 +0000 https://clinicalvalue.com/?p=9362 ...

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Every year, liver cancer claims 740,000 lives worldwide, with 42% of these deaths occurring in China. In China, the 5-year survival for hepatocellular carcinoma (HCC) patients is just 14.4%, and over 80% of liver cancer patients diagnosed are those with Hepatitis B. Despite this alarming statistic, early screening and comprehensive, end-to-end disease management approaches remained limited in China. This created a critical gap in care, one that Zhuhai People’s Hospital in collaboration with Roche, aimed to address with the initiation of Project Pearl in 2022.

Project Pearl is a pioneering multi-stakeholder initiative designed to provide holistic care to patients with chronic liver disease by enabling end-to-end chronic disease management involving healthcare professionals, hospital administration, and payors. At its core, the project leverages on the Liver Integrated Solution, comprising of two key digital solutions:

  • Liver Disease Pathway (LDP), a digital platform streamlining HCC screening workflow and offering a patient portal for better care management
  • Oncology Hub (OH), a clinical workflow for multidisciplinary team meetings and decision support system

This integrated solution empowers clinicians with the right information at the right time, ensuring informed, precise decision-making throughout the patient’s journey.

Let’s explore how the patient’s journey has evolved under this new framework. Upon their first hospital visit, patients with chronic liver disease are registered on the digital solution, and are evaluated with abdominal ultrasound, AFP, PIVKA-II, and GAAD, aimed at early detection of HCC. The patients’ data and reports are synchronized for physicians to view in real time. Meanwhile, risk stratification scores provide physicians with a clearer understanding of each patient’s likelihood of developing liver cancer, allowing for more personalized, periodic surveillance plans. Physicians are able to easily arrange follow-ups with the patients and track their disease progression over time. Beyond the hospital, an interoperable mobile platform extends support with follow-up reminders, report interpretation, patient education, and 1 on 1 consultation. This empowers patients to better understand their condition and also ensures they receive continuous, standardized care, essential for early detection and intervention. For physicians, the new patient journey not only streamlines operations but also enhances clinical effectiveness by enabling early detection, offering curative treatment options, and improving patient outcomes.

The entire clinical and operational workflow from screening and diagnosis and follow-up is now automated, making it easier to manage every step of care delivery. Once patients are diagnosed with HCC, they are seamlessly transitioned into a comprehensive treatment management system. This integrated approach addresses the following challenges that are commonly observed in MDT care delivery. Lack of standardized MDT clinical protocol, absence of robust post-treatment follow-up system, and limited capabilities to analyse and gain insights from treatment data. Upon transition, a patient’s 360 report is automatically generated to show their entire patient history. This empowers them with data-driven insights to deliver clinical, operational and economic outcomes to manage HCC treatment more effectively and confidently.

Ultimately, Project Pearl enables a win for all stakeholders. For patients, early detection and personalized care plans lead to better outcomes. For physicians, streamlines, standardized workflows and digitally-enabled decision-making support clinical practice in a timely and effective manner. For the health system, the project accelerates the goals of “Healthy China 2030”, improving outcomes at reduced costs. By improving both patient outcomes and healthcare efficiency, we are taking significant steps toward a future where liver cancer can be detected early and treated effectively, creating hope for thousands of lives.

Since its launch, Project Pearl has seem promising results. Till date, 4,972 patients had been screened, and 40 cases of HCC had been diagnosed. Remarkably, 39 of those cases were detected at an early stage, offering significantly better chances for curative treatment. These outcomes demonstrate the project’s real-world impact in transforming liver cancer care and improving patient outcomes.

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Cervical cancer survivor shares journey from diagnosis to recovery https://clinicalvalue.com/cervical-cancer-survivor-shares-journey-from-diagnosis-to-recovery/ Mon, 13 May 2024 05:38:25 +0000 https://clinicalvalue.com/?p=8400 ...

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Summer Ng was 24 years old when she was diagnosed with cervical cancer and told she could not become a mother. In this candid fireside chat with Yvonne Ng, founder of the Alliance for Active Action Against HPV (A4HPV), Summer discusses her experience of coping with the diagnosis and charting a path through a medical system that did not have all the answers.

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Cervical cancer survivor stories: Chris Chong Suet Yee https://clinicalvalue.com/chris-chong-cancer-survivor-journey/ Mon, 13 May 2024 05:38:06 +0000 https://clinicalvalue.com/?p=8405 ...

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Cervical cancer is one of the top three cancers diagnosed in Malaysian women. It is also one of the most treatable cancers if detected early, but an acute association with anxiety, fear or pain are common reasons women do not present for screening. This is why so many women in Malaysia are diagnosed with late stage cervical cancer.

In this powerful short film, survivor Chris discusses her battle with cervical cancer. Chris is a Malaysian-Chinese woman with a three year old daughter. She is 34 years old and is currently fighting cervical cancer for the third time. Chris explains how she put off being tested for cervical cancer out of embarrassment and only sought help once she noticed symptoms.

Chris is continuing to fight cervical cancer and she doesn’t want any woman to suffer the way she has. Chris is calling for women worldwide to be screened regularly for cervical cancer, because if caught early, it is one of the most treatable types of cancers.

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Changing the Facts about Cervical Cancer | Thailand https://clinicalvalue.com/changing-the-facts-about-cervical-cancer-thailand/ Mon, 13 May 2024 05:37:36 +0000 https://clinicalvalue.com/?p=8388 ...

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In Thailand, only 53% of Thai women get regular checkups. Ms. Chutiyaphat Santhong is a survivor of Stage III Cervical Cancer who wants to empower other women to learn more about cervical cancer and start prioritising their own health.

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Changing the Facts about Cervical Cancer | Hong Kong https://clinicalvalue.com/changing-the-facts-about-cervical-cancer-hong-kong/ Mon, 13 May 2024 05:37:15 +0000 https://clinicalvalue.com/?p=8393 ...

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Meet Mrs Patricia Chu, BBS, Chairman, The Hong Kong Anti-Cancer Society, Hong Kong who is a powerful advocate for building awareness and influencing policies that support women’s health.

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Changing the Facts about Cervical Cancer | India https://clinicalvalue.com/changing-the-facts-about-cervical-cancer-india/ Mon, 13 May 2024 05:36:53 +0000 https://clinicalvalue.com/?p=8383 ...

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India has one-fifth of the world’s cervical cancer cases, among whom the majority are only diagnosed in stages III and IV. Dr Kiran Coelho, Head of Department of Obstetrics and Gynecology, Lilavati Hospital in India, believes in having a healthcare system with equity and resources for women.

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365 Cancer Prevention Society – Know Your Liver Webinar 2024 https://clinicalvalue.com/365-cancer-prevention-society-know-your-liver-webinar-2024/ Mon, 22 Apr 2024 05:57:55 +0000 https://clinicalvalue.com/?p=8282 ...

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Injection or infusion? How biologic cancer medicines can be given

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Rethinking the delivery of biologics in the treatment of cancer https://clinicalvalue.com/rethinking-the-delivery-of-biologics-in-the-treatment-of-cancer/ Thu, 11 Apr 2024 06:05:53 +0000 https://clinicalvalue.com/?p=8246 ...

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Subcutaneous delivery infographic

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Lung cancer patient journey infographic https://clinicalvalue.com/lung-cancer-patient-journey-infographic/ Mon, 22 May 2023 03:54:47 +0000 https://clinicalvalue.com/?p=6859 ...

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